V/Q Scan

V/Q Scan

  • Tc-MAA (technetium tagged to albumin)

  • Inhaled radiotracer - shows ventilation

    • Xenon 133

      • Short half life - 30 s

      • Low energy ~80 keV

      • 3 phase - wash in, equilibrium, wash out

      • Fat soluble

        • May see uptake in the liver if it is fatty

    • Tc-99m DTPA

      • Energy 140 keV

      • Allows for multiple projections

      • Tracheal clumping

  • IV radiotracer - shows perfusion

    • Tc-MAA (technetium tagged to albumin)

    • Should stay in lungs because it basically gets trapped into capillaries in lung

    • See radiotracer in brain

      • Look for shunt

  • Downscatter

    • Lower energy tracers have to be used first

      • This is because the one with the higher energy will basically decay into the values of the lower energy one and won’t know what the real shit is

    • So for this, the Xenon has to be used before the Tc (the inhaled before the blood portion)

  • When should radiotracer particle amount be decreased

    • Does not mean reduce the dose

    • Basically a more concentrated dose i guess

    • Basically the particles get stuck in and block off the capillaries and don’t want to block more than 0.1% of capillaries

      • So situations where there are less capillaries require less particles such as:

        • Kids

        • Lung resection

        • Pulmonary hypertension

        • Known shunt

  • Normal to have

    • Perfusion slightly less at top of lungs (hence hematogenous shit goes to base of lungs)

    • Ventilation slightly less at bottom of lungs (hence airborne shit goes to top of lungs)

  • PE

    • Normal ventilation

    • Wedge shaped area of perfusion decrease (typically in periphery)

    • Normal perfusion essentially excludes a PE regardless of findings on ventilation portion

  • PIOPED Criteria

    • Criteria for reporting liklihood of having a PE

    • Very low = <5 %

    • Low < 20%

    • Intermediate = <80%

    • High = > 80%

  • Must have a CXR before doing

  • Size

    • Described as a fraction of the segment

    • Small = <25% (do not add the smalls)

    • Moderate = <75%

      • 2 moderate = 1 large

    • Large = > 75%

Air Trapping

  • Will see slightly increased radiotracer uptake in the base of the lungs rather than the apex (note should normally be slightly high inhaled radiotracer in the lung apex)

  • This is for the ventilation portion

  • Not super obvious

Complete lack of uptake in one lung

  • Complete lack of perfusion in one lung

    • DDx

      • Hilar mass

      • Hypoplastic pulmonary artery

      • Mediastinal fibrosis

    • If you see complete lack of perfusion in one lung and normal ventilation that is a cancer eating into the artery

  • Complete lack of ventilation in one lung

  • NOTE: Foreign body in mainstem bronchus will not cause whole lung mismatch

    • This is because there is hypoxic vasoconstriction leading to decrease in blood flow to the non-ventilated lung so the decrease in perfusion and ventilation is the same

Fissure Sign

  • Fluid in fissure causes defect

  • No PE present

References:

Clumping

  • Basically multi-focal hot spots throughout lungs

  • Seen when person injecting draws back on syringe and causes radiotracer to clump

  • No other cause

Triple Match

  • Defect seen on CXR, ventilation & perfusion scans

  • Triple match in lower lobe = Intermediate risk

  • Triple match in upper lobe = low risk